The Development and Maintenance of the Crl:CH!!J(SD)IGSBR Rat Breeding System
نویسنده
چکیده
Systems for genetically standardizing inbred strains of rodents have been well documented. With the internationalization of biomedical research, it has become necessary for multi-national laboratory animal suppliers to globally standardize more commonly used non-inbred toxicology models such as the Sprague Dawley and Hanover Wistar rat stocks. This paper describes one such breeding system, the International Genetic Standard (IGS8) system to produce the Crl:CO8(SO) IGS BR and Crl:WI(Glx/BRLlHan) IGS BR rats for the international biomedical research community.-
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